WELCOME TO THE SHERMAN LABORATORY
CELL BIOLOGY RESEARCH PROGRAM

Philip M. Sherman MD, FRCP(C)

My laboratory is characterizing host epithelial-cell signalling responses after infection with enterohaemorrhagic Escherichia coli O157:H7 and exposure to probiotics. These studies use complementary in vitro models of bacterial adhesion, in vivo animals models of human disease, and clinical research protocols for children and adolescents. An improved understanding of how these microbes interact with host-cell surfaces should lead to the development of novel methods to prevent and treat human disease.